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重組葡激酶Recombinant Staphylokinase
重組葡激酶Recombinant Staphylokinase
重組葡激酶Recombinant Staphylokinase

重組葡激酶Recombinant Staphylokinase

 詳情說明

重組葡激酶Recombinant Staphylokinase

貨號(hào):zk2197

英文名: Recombinant Staphylokinase
別名: SAK, Recombinant
相關(guān)類別:

儲(chǔ)存冷凍:(-20℃)

分子量Approximately 15.6 kDa, a single non-glycosylated polypeptide chain containing 136 amino acids.

規(guī)格:20 UG

產(chǎn)品概述

Staphylokinase is an amino acid enzyme secreted by several species of streptococci. It is a 16 kDa potent plasminogen activator that converts plasminogen into plasmin which can digest fibrin the major constituent of blood thrombi. SAK forms 1:1 complex with plasmin, which is a positive feedback of producing other complexes. Recent studies on the thrombolytic potential of recombinant SAK in achieving early perfusion in myocardial infarction and in the dissolution of platelet-rich clot have clearly established its immense utility in clinical medicine as a thrombolytic agent and suggested that it can be developed as a potent clot-dissolving agent.

使用說明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技術(shù)規(guī)格

Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Purity > 97% by SDS-PAGE and HPLC analyses.
Source Escherichia coli.
Biological Activity Fully biologically active when compared to standard. The specific activity determined by fibrining lysis in agarose plate is 5.0 × 104 IU/mg.
Formulation Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Endotoxin Less than 1 EU/μg of rSAK as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence SSSFDKGKYK KGDDASYFEP TGPYLMVNVT GVDGKRNELL SPRYVEFPIK PGTTLTKEKI EYYVEWALDA TAYKEFRVVE LDPSAKIEVT YYDKNKKKEE TKSFPITEKG FVVPDLSEHI KNPGFNLITK VVIEKK

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