PeproTech重組小鼠IL-1β(無動(dòng)物成分) ,貨號(hào):211-11B
PeproTech重組小鼠IL-1β(無動(dòng)物成分) ,貨號(hào):211-11B
PeproTech重組小鼠IL-1β(無動(dòng)物成分) ,貨號(hào):211-11B
品牌 :PEPROTECH
產(chǎn)地 :美國
貨號(hào): AF-211-11B
貨號(hào):2μg/10μg/1mg
供應(yīng)商: 深圳子科生物科技有限公司
數(shù)量: 大量
英文名: Recombinant Murine IL-1β
保質(zhì)期: 1年以上
保存條件: -20℃
Catalog Number:
AF-211-11B
Synonyms:
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Description:
IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Murine IL-1β is a 17.5 kDa protein containing 153 amino acid residues. Manufactured using all Animal-Free reagents.
AA Sequence:
MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.002 ng/ml, corresponding to a specific activity of ≥ 5 x 108 units/mg.