Synonyms :

Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor

Description :

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant rat SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

Catalog #:

400-22

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

Determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells. The expected ED ₅₀ for this effect is 20 - 40 ng/ml.

Selected References :

Selected List of References Citing This Product

AA Sequence :

MQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV THLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRN FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA

PubMed Link :

SCF+AND+rat

Country of Origin :

USA

Special Sizes: 
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Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.