中文名稱:血小板活化因子抗體
產品貨號:ZIKER-1119R
英文名稱:PAF
別 名:platelet-activating factor; 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate; 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine; 3-sn-Phosphatidylcholine; 1-hexadecyl-2-acetyl, PAF(C16.
規(guī) 格: 100ul
產品類型:藥物與化合物抗體
研究領域:藥物及化合物
抗體來源:Rabbit
克隆類型:Polyclonal
交叉反應: Rat, PAF
產品應用:ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量:0.524kDa
性 狀:Lyophilized or Liquid
濃 度:1mg/ml
免 疫 原:KLH conjugated PAF:
亞 型:IgG
純化方法:affinity purified by Protein A
儲 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹:background:
Platelet-activating factor, a compound that reduces inflammation by increasing permeability of blood vessels and contracting various involuntary muscles such as those in airways. It is a phospholipid with a wide range of proinflammatory actions, is immediately degraded and inactivated in vivo by PAF acetylhydrolase.
SWISS:
N/A
CAS:
74389-68-7
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血小板活化因子(platelet-activating factor,PAF)是一種內源性具有生物活性的磷脂。由中性粒細胞、血小板、肥大細胞、內皮細胞和巨噬細胞產生。除早期發(fā)現它有強烈引起血小板聚集和脫顆粒作用外,近年來的研究發(fā)現它還具有廣泛的生物活性,作為一種獨特的細胞因子參與體內多種生理、病理過程,包括激活中性粒細胞,使其聚集、趨化、釋放氧自由基和白三烯,抑制T細胞增殖,刺激B細胞合成IgG和IgE,抑制心肌收縮力,增加血管通透性,引起體循環(huán)血壓下降和肺動脈高壓等。由于它具有廣泛的高強度的生物活性,故PAF被認為是與過敏反應有關的關鍵性介質之一。